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Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis

BACKGROUND: Diabetes is the seventh leading cause of death in the USA, and disruption of circadian rhythms is gaining recognition as a contributing factor to disease prevalence. This disease is characterized by hyperglycemia and glucose intolerance and symptoms caused by failure to produce and/or re...

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Detalles Bibliográficos
Autores principales: Harfmann, Brianna D., Schroder, Elizabeth A., Kachman, Maureen T., Hodge, Brian A., Zhang, Xiping, Esser, Karyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969979/
https://www.ncbi.nlm.nih.gov/pubmed/27486508
http://dx.doi.org/10.1186/s13395-016-0082-x