Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?

A growing field of evidence suggests the involvement of oncogenic receptor tyrosine kinases (RTKs) in the transformation of malignant cells. Constitutive and abnormal activation of RTKs may occur in tumors either through hyperactivation of mutated RTKs or via functional upregulation by RTK-coding ge...

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Detalles Bibliográficos
Autores principales: Aveic, Sanja, Tonini, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970224/
https://www.ncbi.nlm.nih.gov/pubmed/27486382
http://dx.doi.org/10.1186/s12935-016-0341-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970224/
https://www.ncbi.nlm.nih.gov/pubmed/27486382
http://dx.doi.org/10.1186/s12935-016-0341-2

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