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Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation
BACKGROUND: Protein arginine methyltransferase 5 (PRMT5) catalyzes the formation of symmetrical dimethylation of arginine residues in proteins. WD repeat domain 77 (WDR77), also known as p44, MEP50, or WD45, forms a stoichiometric complex with PRMT5. The PRMT5/p44 complex is required for cellular pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970276/ https://www.ncbi.nlm.nih.gov/pubmed/27480244 http://dx.doi.org/10.1186/s12885-016-2632-3 |