Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation

BACKGROUND: Protein arginine methyltransferase 5 (PRMT5) catalyzes the formation of symmetrical dimethylation of arginine residues in proteins. WD repeat domain 77 (WDR77), also known as p44, MEP50, or WD45, forms a stoichiometric complex with PRMT5. The PRMT5/p44 complex is required for cellular pr...

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Detalles Bibliográficos
Autores principales: Sheng, Xiumei, Wang, Zhengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970276/
https://www.ncbi.nlm.nih.gov/pubmed/27480244
http://dx.doi.org/10.1186/s12885-016-2632-3

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