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Assembly and activation of dynein–dynactin by the cargo adaptor protein Hook3
Metazoan cytoplasmic dynein moves processively along microtubules with the aid of dynactin and an adaptor protein that joins dynein and dynactin into a stable ternary complex. Here, we examined how Hook3, a cargo adaptor involved in Golgi and endosome transport, forms a motile dynein–dynactin comple...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970328/ https://www.ncbi.nlm.nih.gov/pubmed/27482052 http://dx.doi.org/10.1083/jcb.201604002 |