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The importance of serine metabolism in cancer

Serine metabolism is frequently dysregulated in cancers; however, the benefit that this confers to tumors remains controversial. In many cases, extracellular serine alone is sufficient to support cancer cell proliferation, whereas some cancer cells increase serine synthesis from glucose and require...

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Detalles Bibliográficos
Autores principales: Mattaini, Katherine R., Sullivan, Mark R., Vander Heiden, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970329/
https://www.ncbi.nlm.nih.gov/pubmed/27458133
http://dx.doi.org/10.1083/jcb.201604085