Cargando…
The importance of serine metabolism in cancer
Serine metabolism is frequently dysregulated in cancers; however, the benefit that this confers to tumors remains controversial. In many cases, extracellular serine alone is sufficient to support cancer cell proliferation, whereas some cancer cells increase serine synthesis from glucose and require...
Autores principales: | Mattaini, Katherine R., Sullivan, Mark R., Vander Heiden, Matthew G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970329/ https://www.ncbi.nlm.nih.gov/pubmed/27458133 http://dx.doi.org/10.1083/jcb.201604085 |
Ejemplares similares
-
Increased PHGDH expression promotes aberrant melanin accumulation
por: Mattaini, Katherine R., et al.
Publicado: (2019) -
Human Phosphoglycerate Dehydrogenase
Produces the
Oncometabolite d-2-Hydroxyglutarate
por: Fan, Jing, et al.
Publicado: (2014) -
An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation
por: Mattaini, Katherine R, et al.
Publicado: (2015) -
Serine and glycine metabolism in cancer()
por: Amelio, Ivano, et al.
Publicado: (2014) -
Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies
por: Muir, Alexander, et al.
Publicado: (2018)