Cargando…

Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins

MicroRNAs (miRNAs) are potentially attractive candidates for cancer therapy. However, their therapeutic application is limited by lack of availability of an efficient delivery system to stably deliver these potent molecules intracellularly to cancer cells while avoiding healthy cells. We developed a...

Descripción completa

Detalles Bibliográficos
Autores principales: Perepelyuk, Maryna, Maher, Christina, Lakshmikuttyamma, Ashakumary, Shoyele, Sunday A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970448/
https://www.ncbi.nlm.nih.gov/pubmed/27555773
http://dx.doi.org/10.2147/IJN.S110488