The synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation

Reductive drug-functionalized gold nanoparticles (AuNPs) have been proposed to enhance the damage of X-rays to cells through improving hydroxyl radical production by secondary electrons. In this work, polyethylene glycol-capped AuNPs were conjugated with tirapazamine (TPZ) moiety, and then thioctyl...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Liu, Yan, Zhang, Pengcheng, Jin, Xiaodong, Zheng, Xiaogang, Ye, Fei, Chen, Weiqiang, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970453/
https://www.ncbi.nlm.nih.gov/pubmed/27555772
http://dx.doi.org/10.2147/IJN.S105348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970453/
https://www.ncbi.nlm.nih.gov/pubmed/27555772
http://dx.doi.org/10.2147/IJN.S105348

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