Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

Enhancing repair of myelin is an important, but still elusive therapeutic goal in many neurological disorders(1). In Multiple Sclerosis (MS), an inflammatory demyelinating disease, endogenous remyelination does occur but is frequently insufficient to restore function. Both parenchymal oligodendrocyt...

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Detalles Bibliográficos
Autores principales: Samanta, Jayshree, Grund, Ethan M., Silva, Hernandez M., Lafaille, Juan J., Fishell, Gord, Salzer, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970518/
https://www.ncbi.nlm.nih.gov/pubmed/26416758
http://dx.doi.org/10.1038/nature14957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970518/
https://www.ncbi.nlm.nih.gov/pubmed/26416758
http://dx.doi.org/10.1038/nature14957

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