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Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1

During meiosis, programmed double strand breaks (DSBs) are repaired preferentially between homologs to generate crossovers that promote proper chromosome segregation at Meiosis I. In many organisms, there are two strand exchange proteins, Rad51 and the meiosis-specific Dmc1, required for interhomolo...

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Detalles Bibliográficos
Autores principales: Callender, Tracy L., Laureau, Raphaelle, Wan, Lihong, Chen, Xiangyu, Sandhu, Rima, Laljee, Saif, Zhou, Sai, Suhandynata, Ray T., Prugar, Evelyn, Gaines, William A., Kwon, YoungHo, Börner, G. Valentin, Nicolas, Alain, Neiman, Aaron M., Hollingsworth, Nancy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970670/
https://www.ncbi.nlm.nih.gov/pubmed/27483004
http://dx.doi.org/10.1371/journal.pgen.1006226