FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones

Netrin-1 is an essential extracellular chemoattractant that signals through its receptor DCC to guide commissural axon extension in the embryonic spinal cord. DCC directs the organization of F-actin in growth cones by activating an intracellular protein complex that includes the Rho GTPase Cdc42, a...

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Detalles Bibliográficos
Autores principales: Rappaz, Benjamin, Lai Wing Sun, Karen, Correia, James P., Wiseman, Paul W., Kennedy, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970703/
https://www.ncbi.nlm.nih.gov/pubmed/27482713
http://dx.doi.org/10.1371/journal.pone.0159405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970703/
https://www.ncbi.nlm.nih.gov/pubmed/27482713
http://dx.doi.org/10.1371/journal.pone.0159405

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