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The Prostaglandin E(2)-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

Rickettsial agents are sensed by pattern recognition receptors but lack pathogen-associated molecular patterns commonly observed in facultative intracellular bacteria. Due to these molecular features, the order Rickettsiales can be used to uncover broader principles of bacterial immunity. Here, we u...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowei, Shaw, Dana K., Hammond, Holly L., Sutterwala, Fayyaz S., Rayamajhi, Manira, Shirey, Kari Ann, Perkins, Darren J., Bonventre, Joseph V., Velayutham, Thangam S., Evans, Sean M., Rodino, Kyle G., VieBrock, Lauren, Scanlon, Karen M., Carbonetti, Nicholas H., Carlyon, Jason A., Miao, Edward A., McBride, Jere W., Kotsyfakis, Michail, Pedra, Joao H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970705/
https://www.ncbi.nlm.nih.gov/pubmed/27482714
http://dx.doi.org/10.1371/journal.ppat.1005803