Immunologic Function and Molecular Insight of Recombinant Interleukin-18

In recent years, cytokine-mediated therapy has emerged as further advance alternative in cancer therapy. Interleukin-18 (IL-18) has exhibited interesting anti-cancer properties especially when combined with IL-12. We engineered IL-18 in order to improve its activity using single point mutagenesis. I...

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Detalles Bibliográficos
Autores principales: Saetang, Jirakrit, Puseenam, Aekkachai, Roongsawang, Niran, Voravuthikunchai, Supayang Piyawan, Sangkhathat, Surasak, Tipmanee, Varomyalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970725/
https://www.ncbi.nlm.nih.gov/pubmed/27483370
http://dx.doi.org/10.1371/journal.pone.0160321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970725/
https://www.ncbi.nlm.nih.gov/pubmed/27483370
http://dx.doi.org/10.1371/journal.pone.0160321

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