Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential

The high-risk Human Papillomavirus (HPV) E6 oncoproteins are characterised by the presence of a class I PDZ-binding motif (PBM) on their extreme carboxy termini. The PBM is present on the E6 proteins derived from all cancer-causing HPV types, but can also be found on some related non-cancer-causing...

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Detalles Bibliográficos
Autores principales: Thomas, Miranda, Myers, Michael P., Massimi, Paola, Guarnaccia, Corrado, Banks, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970744/
https://www.ncbi.nlm.nih.gov/pubmed/27483446
http://dx.doi.org/10.1371/journal.ppat.1005766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970744/
https://www.ncbi.nlm.nih.gov/pubmed/27483446
http://dx.doi.org/10.1371/journal.ppat.1005766

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