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Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential
The high-risk Human Papillomavirus (HPV) E6 oncoproteins are characterised by the presence of a class I PDZ-binding motif (PBM) on their extreme carboxy termini. The PBM is present on the E6 proteins derived from all cancer-causing HPV types, but can also be found on some related non-cancer-causing...
Autores principales: | Thomas, Miranda, Myers, Michael P., Massimi, Paola, Guarnaccia, Corrado, Banks, Lawrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970744/ https://www.ncbi.nlm.nih.gov/pubmed/27483446 http://dx.doi.org/10.1371/journal.ppat.1005766 |
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