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CFTR Deletion in Mouse Testis Induces VDAC1 Mediated Inflammatory Pathway Critical for Spermatogenesis

Cystic fibrosis is the most common genetic disease among Caucasians and affects tissues including lung, pancreas and reproductive tracts. It has been shown that Endoplasmic Reticulum (ER) stress and heat shock response are two major deregulated functional modules related to CFTR dysfunction. To iden...

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Detalles Bibliográficos
Autores principales: Yan, Chen, Lang, Qin, Huijuan, Liao, Jiang, Xie, Ming, Yang, Huaqin, Sun, Wenming, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970767/
https://www.ncbi.nlm.nih.gov/pubmed/27483469
http://dx.doi.org/10.1371/journal.pone.0158994