Improved Metabolic Models for E. coli and Mycoplasma genitalium from GlobalFit, an Algorithm That Simultaneously Matches Growth and Non-Growth Data Sets

Constraint-based metabolic modeling methods such as Flux Balance Analysis (FBA) are routinely used to predict the effects of genetic changes and to design strains with desired metabolic properties. The major bottleneck in modeling genome-scale metabolic systems is the establishment and manual curati...

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Detalles Bibliográficos
Autores principales: Hartleb, Daniel, Jarre, Florian, Lercher, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970803/
https://www.ncbi.nlm.nih.gov/pubmed/27482704
http://dx.doi.org/10.1371/journal.pcbi.1005036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970803/
https://www.ncbi.nlm.nih.gov/pubmed/27482704
http://dx.doi.org/10.1371/journal.pcbi.1005036

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