Effect of food on the pharmacokinetics of TAS‐102 and its efficacy and safety in patients with advanced solid tumors

TAS‐102, a novel oral antitumor agent, consists of trifluridine and tipiracil hydrochloride (molar ratio, 1:0.5). We investigated the effects of food on trifluridine and tipiracil hydrochloride. The efficacy and safety of TAS‐102 were evaluated in patients with advanced solid tumors. We analyzed dru...

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Detalles Bibliográficos
Autores principales: Yoshino, Takayuki, Kojima, Takashi, Bando, Hideaki, Yamazaki, Tomoko, Naito, Yoichi, Mukai, Hirofumi, Fuse, Nozomu, Goto, Koichi, Ito, Yuko, Doi, Toshihiko, Ohtsu, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970833/
https://www.ncbi.nlm.nih.gov/pubmed/26918279
http://dx.doi.org/10.1111/cas.12912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970833/
https://www.ncbi.nlm.nih.gov/pubmed/26918279
http://dx.doi.org/10.1111/cas.12912

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