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Selective activator protein‐1 inhibitor T‐5224 prevents lymph node metastasis in an oral cancer model

Activator protein‐1 (AP‐1) is a transcriptional factor that regulates the expression of various genes associated with tumor invasion and migration. The purpose of our study was to assess the therapeutic effects of a novel selective AP‐1 inhibitor, T‐5224, in preventing lymph node metastasis in head...

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Detalles Bibliográficos
Autores principales: Kamide, Daisuke, Yamashita, Taku, Araki, Koji, Tomifuji, Masayuki, Tanaka, Yuya, Tanaka, Shingo, Shiozawa, Shunichi, Shiotani, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970834/
https://www.ncbi.nlm.nih.gov/pubmed/26918517
http://dx.doi.org/10.1111/cas.12914