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Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching

Antibody class switching is a feature of the adaptive immune system which enables diversification of the effector properties of antibodies. Even though class switching is essential for mounting a protective response to pathogens, the in vivo patterns and lineage characteristics of antibody class swi...

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Detalles Bibliográficos
Autores principales: Horns, Felix, Vollmers, Christopher, Croote, Derek, Mackey, Sally F, Swan, Gary E, Dekker, Cornelia L, Davis, Mark M, Quake, Stephen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970870/
https://www.ncbi.nlm.nih.gov/pubmed/27481325
http://dx.doi.org/10.7554/eLife.16578