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Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes
In addition to the helical nature of double-stranded DNA and RNA, single-stranded oligonucleotides can arrange themselves into tridimensional structures containing loops, bulges, internal hairpins and many other motifs. This ability has been used for more than two decades to generate oligonucleotide...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971091/ https://www.ncbi.nlm.nih.gov/pubmed/27536656 http://dx.doi.org/10.3389/fchem.2016.00033 |