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Vanadate Impedes Adipogenesis in Mesenchymal Stem Cells Derived from Different Depots within Bone

Glucocorticoid-induced osteoporosis (GIO) is associated with an increase in bone marrow adiposity, which skews the differentiation of mesenchymal stem cell (MSC) progenitors away from osteoblastogenesis and toward adipogenesis. We have previously found that vanadate, a non-specific protein tyrosine...

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Detalles Bibliográficos
Autores principales: Jacobs, Frans Alexander, Sadie-Van Gijsen, Hanél, van de Vyver, Mari, Ferris, William Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971437/
https://www.ncbi.nlm.nih.gov/pubmed/27536268
http://dx.doi.org/10.3389/fendo.2016.00108