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Anti-photoaging properties of the phosphodiesterase 3 inhibitor cilostazol in ultraviolet B-irradiated hairless mice

We investigated whether cilostazol, an activator of cyclic adenosine monophosphate (cAMP)-dependent intracellular signaling, could inhibit ultraviolet B (UVB) irradiation-induced photoaging in HR-1 hairless mice. Cilostazol decreased wrinkle formation and skin thickness in UVB-irradiated mice, as we...

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Detalles Bibliográficos
Autores principales: Kim, Ha Neui, Gil, Chan Hee, Kim, Yu Ri, Shin, Hwa Kyoung, Choi, Byung Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971469/
https://www.ncbi.nlm.nih.gov/pubmed/27484958
http://dx.doi.org/10.1038/srep31169