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High fat diet-induced TGF-β/Gbb signaling provokes insulin resistance through the tribbles expression

Hyperglycemia, hyperlipidemia, and insulin resistance are hallmarks of obesity-induced type 2 diabetes, which is often caused by a high-fat diet (HFD). However, the molecular mechanisms underlying HFD-induced insulin resistance have not been elucidated in detail. In this study, we established a Dros...

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Detalles Bibliográficos
Autores principales: Hong, Seung-Hyun, Kang, Moonyoung, Lee, Kyu-Sun, Yu, Kweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971497/
https://www.ncbi.nlm.nih.gov/pubmed/27484164
http://dx.doi.org/10.1038/srep30265