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Optogenetic and chemogenetic strategies for sustained inhibition of pain

Spatially targeted, genetically-specific strategies for sustained inhibition of nociceptors may help transform pain science and clinical management. Previous optogenetic strategies to inhibit pain have required constant illumination, and chemogenetic approaches in the periphery have not been shown t...

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Detalles Bibliográficos
Autores principales: Iyer, Shrivats M., Vesuna, Sam, Ramakrishnan, Charu, Huynh, Karen, Young, Stephanie, Berndt, Andre, Lee, Soo Yeun, Gorini, Christopher J., Deisseroth, Karl, Delp, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971509/
https://www.ncbi.nlm.nih.gov/pubmed/27484850
http://dx.doi.org/10.1038/srep30570