Angelman syndrome-derived neurons display late onset of paternal UBE3A silencing

Genomic imprinting is an epigenetic phenomenon resulting in parent-of-origin-specific gene expression that is regulated by a differentially methylated region. Gene mutations or failures in the imprinting process lead to the development of imprinting disorders, such as Angelman syndrome. The symptoms...

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Detalles Bibliográficos
Autores principales: Stanurova, Jana, Neureiter, Anika, Hiber, Michaela, de Oliveira Kessler, Hannah, Stolp, Kristin, Goetzke, Roman, Klein, Diana, Bankfalvi, Agnes, Klump, Hannes, Steenpass, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971516/
https://www.ncbi.nlm.nih.gov/pubmed/27484051
http://dx.doi.org/10.1038/srep30792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971516/
https://www.ncbi.nlm.nih.gov/pubmed/27484051
http://dx.doi.org/10.1038/srep30792

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