Cargando…

Arsenite-loaded nanoparticles inhibit PARP-1 to overcome multidrug resistance in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is one of the highest incidences in cancers; however, traditional chemotherapy often suffers from low efficiency caused by drug resistance. Herein, we report an arsenite-loaded dual-drug (doxorubicin and arsenic trioxide, i.e., DOX and ATO) nanomedicine system (FeAsO(x...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Hanyu, Zhang, Zongjun, Chi, Xiaoqin, Zhao, Zhenghuan, Huang, Dengtong, Jin, Jianbin, Gao, Jinhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971527/
https://www.ncbi.nlm.nih.gov/pubmed/27484730
http://dx.doi.org/10.1038/srep31009