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Arsenite-loaded nanoparticles inhibit PARP-1 to overcome multidrug resistance in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is one of the highest incidences in cancers; however, traditional chemotherapy often suffers from low efficiency caused by drug resistance. Herein, we report an arsenite-loaded dual-drug (doxorubicin and arsenic trioxide, i.e., DOX and ATO) nanomedicine system (FeAsO(x...

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Detalles Bibliográficos
Autores principales:	Liu, Hanyu, Zhang, Zongjun, Chi, Xiaoqin, Zhao, Zhenghuan, Huang, Dengtong, Jin, Jianbin, Gao, Jinhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971527/ https://www.ncbi.nlm.nih.gov/pubmed/27484730 http://dx.doi.org/10.1038/srep31009

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