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Macromolecular crowding explains overflow metabolism in cells

Overflow metabolism is a metabolic phenotype of cells characterized by mixed oxidative phosphorylation (OxPhos) and fermentative glycolysis in the presence of oxygen. Recently, it was proposed that a combination of a protein allocation constraint and a higher proteome fraction cost of energy generat...

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Detalles Bibliográficos
Autores principales: Vazquez, Alexei, Oltvai, Zoltán N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971534/
https://www.ncbi.nlm.nih.gov/pubmed/27484619
http://dx.doi.org/10.1038/srep31007