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Quality of life effects of androgen deprivation therapy in a prostate cancer cohort in New Zealand: can we minimize effects using a stratification based on the aldo-keto reductase family 1, member C3 rs12529 gene polymorphism?

BACKGROUND: Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient’s health-related quality of life (HRQoL). The current study aims to test whether a genetic stratif...

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Detalles Bibliográficos
Autores principales: Karunasinghe, Nishi, Zhu, Yifei, Han, Dug Yeo, Lange, Katja, Zhu, Shuotun, Wang, Alice, Ellett, Stephanie, Masters, Jonathan, Goudie, Megan, Keogh, Justin, Benjamin, Benji, Holmes, Michael, Ferguson, Lynnette R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971639/
https://www.ncbi.nlm.nih.gov/pubmed/27485119
http://dx.doi.org/10.1186/s12894-016-0164-4