Recapitulating epithelial tumor microenvironment in vitro using three dimensional tri-culture of human epithelial, endothelial, and mesenchymal cells

BACKGROUND: Three-dimensional (3-D) cultures of cancer cells can potentially bridge the gap between 2-D drug screening and in vivo xenografts. The objective of this study was to characterize the cellular and extracellular matrix characteristics of spheroids composed of human lung epithelial cells (e...

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Detalles Bibliográficos
Autores principales: Lamichhane, Surya P., Arya, Neha, Kohler, Esther, Xiang, Shengnan, Christensen, Jon, Shastri, V. Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971675/
https://www.ncbi.nlm.nih.gov/pubmed/27484993
http://dx.doi.org/10.1186/s12885-016-2634-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971675/
https://www.ncbi.nlm.nih.gov/pubmed/27484993
http://dx.doi.org/10.1186/s12885-016-2634-1

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