Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial

BACKGROUND: Septic shock has a 90-day mortality risk of up to 50 %. The hemodynamic targets, including mean arterial pressure (MAP) are not based on robust clinical data. Both severe hypotension and high doses of vasopressors may be harmful. Hence, re-evaluation of hemodynamic targets in septic shoc...

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Detalles Bibliográficos
Autores principales: Pettilä, Ville, Merz, Tobias, Wilkman, Erika, Perner, Anders, Karlsson, Sari, Lange, Theis, Hästbacka, Johanna, Hjortrup, Peter Buhl, Kuitunen, Anne, Jakob, Stephan M., Takala, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971711/
https://www.ncbi.nlm.nih.gov/pubmed/27484695
http://dx.doi.org/10.1186/s13063-016-1515-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971711/
https://www.ncbi.nlm.nih.gov/pubmed/27484695
http://dx.doi.org/10.1186/s13063-016-1515-x

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