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Synaptic plasticity and spatial working memory are impaired in the CD mouse model of Williams-Beuren syndrome

Mice heterozygous for a complete deletion (CD) equivalent to the most common deletion found in individuals with Williams-Beuren syndrome (WBS) recapitulate relevant features of the neurocognitive phenotype, such as hypersociability, along with some neuroanatomical alterations in specific brain areas...

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Detalles Bibliográficos
Autores principales: Borralleras, Cristina, Mato, Susana, Amédée, Thierry, Matute, Carlos, Mulle, Christophe, Pérez-Jurado, Luis A., Campuzano, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971717/
https://www.ncbi.nlm.nih.gov/pubmed/27485321
http://dx.doi.org/10.1186/s13041-016-0258-7