Protective Effect of Thymoquinone against Cyclophosphamide-Induced Hemorrhagic Cystitis through Inhibiting DNA Damage and Upregulation of Nrf2 Expression

Cyclophosphamide (CYP) induced hemorrhagic cystitis is a dose-limiting side effect involving increased oxidative stress, inflammatory cytokines and suppressed activity of nuclear factor related erythroid 2-related factor (Nrf2). Thymoquinone (TQ), an active constituent of Nigella sativa seeds, is re...

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Detalles Bibliográficos
Autores principales: Gore, Prashant R., Prajapati, Chaitali P., Mahajan, Umesh B., Goyal, Sameer N., Belemkar, Sateesh, Ojha, Shreesh, Patil, Chandragouda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971733/
https://www.ncbi.nlm.nih.gov/pubmed/27489498
http://dx.doi.org/10.7150/ijbs.15781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971733/
https://www.ncbi.nlm.nih.gov/pubmed/27489498
http://dx.doi.org/10.7150/ijbs.15781

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