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Protective Effect of Thymoquinone against Cyclophosphamide-Induced Hemorrhagic Cystitis through Inhibiting DNA Damage and Upregulation of Nrf2 Expression
Cyclophosphamide (CYP) induced hemorrhagic cystitis is a dose-limiting side effect involving increased oxidative stress, inflammatory cytokines and suppressed activity of nuclear factor related erythroid 2-related factor (Nrf2). Thymoquinone (TQ), an active constituent of Nigella sativa seeds, is re...
Autores principales: | Gore, Prashant R., Prajapati, Chaitali P., Mahajan, Umesh B., Goyal, Sameer N., Belemkar, Sateesh, Ojha, Shreesh, Patil, Chandragouda R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971733/ https://www.ncbi.nlm.nih.gov/pubmed/27489498 http://dx.doi.org/10.7150/ijbs.15781 |
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