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Integrative analysis with ChIP-seq advances the limits of transcript quantification from RNA-seq
RNA-seq is currently the technology of choice for global measurement of transcript abundances in cells. Despite its successes, isoform-level quantification remains difficult because short RNA-seq reads are often compatible with multiple alternatively spliced isoforms. Existing methods rely heavily o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971760/ https://www.ncbi.nlm.nih.gov/pubmed/27405803 http://dx.doi.org/10.1101/gr.199174.115 |