High-throughput functional comparison of promoter and enhancer activities

Promoters initiate RNA synthesis, and enhancers stimulate promoter activity. Whether promoter and enhancer activities are encoded distinctly in DNA sequences is unknown. We measured the enhancer and promoter activities of thousands of DNA fragments transduced into mouse neurons. We focused on genomi...

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Detalles Bibliográficos
Autores principales: Nguyen, Thomas A., Jones, Richard D., Snavely, Andrew R., Pfenning, Andreas R., Kirchner, Rory, Hemberg, Martin, Gray, Jesse M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971761/
https://www.ncbi.nlm.nih.gov/pubmed/27311442
http://dx.doi.org/10.1101/gr.204834.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971761/
https://www.ncbi.nlm.nih.gov/pubmed/27311442
http://dx.doi.org/10.1101/gr.204834.116

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