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High-throughput functional comparison of promoter and enhancer activities
Promoters initiate RNA synthesis, and enhancers stimulate promoter activity. Whether promoter and enhancer activities are encoded distinctly in DNA sequences is unknown. We measured the enhancer and promoter activities of thousands of DNA fragments transduced into mouse neurons. We focused on genomi...
Autores principales: | Nguyen, Thomas A., Jones, Richard D., Snavely, Andrew R., Pfenning, Andreas R., Kirchner, Rory, Hemberg, Martin, Gray, Jesse M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971761/ https://www.ncbi.nlm.nih.gov/pubmed/27311442 http://dx.doi.org/10.1101/gr.204834.116 |
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