Does PTEN gene mutation play any role in Li-Fraumeni syndrome

Background: Li-Fraumeni syndrome (LFS) is one of the most serious hereditary cancer syndromes with a high risk of malignancy in childhood. This syndrome is an autosomal dominant cancer predisposing syndrome due to a germline mutation in the TP53 tumor suppressor gene. Methods: In this study, a repre...

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Detalles Bibliográficos
Autores principales: Akouchekian, Mansoureh, Hemati, Simin, Jafari, Davood, Jalilian, Nazanin, Dehghan Manshadi, Masoumeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972054/
https://www.ncbi.nlm.nih.gov/pubmed/27493922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972054/
https://www.ncbi.nlm.nih.gov/pubmed/27493922

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