Cargando…

First-in-Human Phase 1 Trial of Agarose Beads Containing Murine RENCA Cells in Advanced Solid Tumors

PURPOSE: Agarose macrobeads containing mouse renal adenocarcinoma cells (RMBs) release factors, suppressing the growth of cancer cells and prolonging survival in spontaneous or induced tumor animals, mediated, in part, by increased levels of myocyte-enhancing factor (MEF2D) via EGFR-and AKT-signalin...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Barry H., Parikh, Tapan, Andrada, Zoe P., Fahey, Thomas J., Berman, Nathaniel, Wiles, Madeline, Nazarian, Angelica, Thomas, Joanne, Arreglado, Anna, Akahoho, Eugene, Wolf, David J., Levine, Daniel M., Parker, Thomas S., Gazda, Lawrence S., Ocean, Allyson J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972125/
https://www.ncbi.nlm.nih.gov/pubmed/27499645
http://dx.doi.org/10.4137/CGM.S39442