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Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters

Antisense transcription is a prevalent feature at mammalian promoters. Previous studies have primarily focused on antisense transcription initiating upstream of genes. Here, we characterize promoter-proximal antisense transcription downstream of gene transcription starts sites in human breast cancer...

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Detalles Bibliográficos
Autores principales: Lavender, Christopher A., Cannady, Kimberly R., Hoffman, Jackson A., Trotter, Kevin W., Gilchrist, Daniel A., Bennett, Brian D., Burkholder, Adam B., Burd, Craig J., Fargo, David C., Archer, Trevor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972320/
https://www.ncbi.nlm.nih.gov/pubmed/27487356
http://dx.doi.org/10.1371/journal.pgen.1006224