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Differential Effects of E2 on MAPK Activity in the Brain and Heart of Aged Female Rats

Aging and the coincident loss of circulating estrogens at menopause lead to increased risks for neurological and cardiovascular pathologies. Clinical studies show that estrogen therapy (ET) can be beneficial in mitigating these negative effects, in both the brain and heart, when it is initiated shor...

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Detalles Bibliográficos
Autores principales: Pinceti, Elena, Shults, Cody L., Rao, Yathindar S., Pak, Toni R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972350/
https://www.ncbi.nlm.nih.gov/pubmed/27487271
http://dx.doi.org/10.1371/journal.pone.0160276