RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord

ALS is a rapidly progressive, devastating neurodegenerative illness of adults that produces disabling weakness and spasticity arising from death of lower and upper motor neurons. No meaningful therapies exist to slow ALS progression, and molecular insights into pathogenesis and progression are sorel...

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Detalles Bibliográficos
Autores principales: Brohawn, David G., O’Brien, Laura C., Bennett, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972368/
https://www.ncbi.nlm.nih.gov/pubmed/27487029
http://dx.doi.org/10.1371/journal.pone.0160520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972368/
https://www.ncbi.nlm.nih.gov/pubmed/27487029
http://dx.doi.org/10.1371/journal.pone.0160520

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