Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension

BACKGROUND AND AIMS: Infants with Down syndrome (DS) or Trisomy 21, are at high risk for developing pulmonary arterial hypertension (PAH), but mechanisms that increase susceptibility are poorly understood. Laboratory studies have shown that early disruption of angiogenesis during development impairs...

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Detalles Bibliográficos
Autores principales: Galambos, Csaba, Minic, Angela D., Bush, Douglas, Nguyen, Dominique, Dodson, Blair, Seedorf, Gregory, Abman, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972384/
https://www.ncbi.nlm.nih.gov/pubmed/27487163
http://dx.doi.org/10.1371/journal.pone.0159005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972384/
https://www.ncbi.nlm.nih.gov/pubmed/27487163
http://dx.doi.org/10.1371/journal.pone.0159005

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