Cargando…

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

Protein kinase B (AKT) phosphorylates numerous substrates on the consensus motif RXRXXpS/T, a docking site for 14-3-3 interactions. To identify novel AKT-induced phosphorylation events following B cell receptor (BCR) activation, we performed proteomics, biochemical and bioinformatics analyses. Phosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammad, Dara K., Ali, Raja H., Turunen, Janne J., Nore, Beston F., Smith, C. I. Edvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972398/
https://www.ncbi.nlm.nih.gov/pubmed/27487157
http://dx.doi.org/10.1371/journal.pone.0160255