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B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

Protein kinase B (AKT) phosphorylates numerous substrates on the consensus motif RXRXXpS/T, a docking site for 14-3-3 interactions. To identify novel AKT-induced phosphorylation events following B cell receptor (BCR) activation, we performed proteomics, biochemical and bioinformatics analyses. Phosp...

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Detalles Bibliográficos
Autores principales:	Mohammad, Dara K., Ali, Raja H., Turunen, Janne J., Nore, Beston F., Smith, C. I. Edvard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972398/ https://www.ncbi.nlm.nih.gov/pubmed/27487157 http://dx.doi.org/10.1371/journal.pone.0160255

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