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Distinct myeloid progenitor differentiation pathways identified through single cell RNA sequencing
According to current models for hematopoiesis, lymphoid-primed multi-potent progenitors (LMPPs; Lin(−)Sca-1(+)c-Kit(+)CD34(+)Flt3(hi)) and common myeloid progenitors (CMPs; Lin(−)Sca-1(+)c-Kit(+)CD34(+)CD41(hi)) establish an early branch point for separate lineage commitment pathways from hematopoie...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972405/ https://www.ncbi.nlm.nih.gov/pubmed/27043410 http://dx.doi.org/10.1038/ni.3412 |