Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice

After using a self-inactivating lentivirus for non-targeted insertional mutagenesis in mice, we identified a transgenic family with a recessive mutation that resulted in reduced fertility in homozygous transgenic mice. The lentiviral integration site was amplified by inverse PCR. Sequencing revealed...

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Detalles Bibliográficos
Autores principales: Fu, Chun, Begum, Khurshida, Jordan, Philip W., He, Yan, Overbeek, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972424/
https://www.ncbi.nlm.nih.gov/pubmed/27486799
http://dx.doi.org/10.1371/journal.pone.0159800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972424/
https://www.ncbi.nlm.nih.gov/pubmed/27486799
http://dx.doi.org/10.1371/journal.pone.0159800

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