In Vitro Inhibition of NFAT5-Mediated Induction of CCL2 in Hyperosmotic Conditions by Cyclosporine and Dexamethasone on Human HeLa-Modified Conjunctiva-Derived Cells

PURPOSE: To investigate the pro-inflammatory intracellular mechanisms induced by an in vitro model of dry eye disease (DED) on a Hela-modified conjunctiva-derived cells in hyperosmolarity (HO) stress conditions. This study focused on CCL2 induction and explored the implications of the nuclear factor...

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Detalles Bibliográficos
Autores principales: Warcoin, Elise, Baudouin, Christophe, Gard, Carole, Brignole-Baudouin, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972436/
https://www.ncbi.nlm.nih.gov/pubmed/27486749
http://dx.doi.org/10.1371/journal.pone.0159983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972436/
https://www.ncbi.nlm.nih.gov/pubmed/27486749
http://dx.doi.org/10.1371/journal.pone.0159983

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